Comparative efficacy of ultrasound-guided intra-articular injection of platelet-rich plasma (PRP), hydrolyzed type I collagen, and hyaluronic acid in patients with knee osteoarthritis: a randomized controlled trial.
Multiple knee arthritis treatments showed significant improvement, expanding options for patients seeking relief from joint pain.
BACKGROUND: Intra-articular therapies are widely used for knee osteoarthritis (KOA), but direct comparisons between emerging biomaterials such as hydrolyzed collagen (HC) and established options like platelet-rich plasma... All groups showed significant improvements (p < 0.001).
What the study was
- Study design
- Randomized study
- Population
- patients
- Sample size
- 135
- Category
- Other
- Maturity
- Exploratory
- Journal
- Future science OA
Why it surfaced
Score 7/10 [PROMISING_PRELIMINARY]: Randomized study (Journal Article) matched 'Sentinel'. Components — novelty:1/3, relevance:3/3, design:2/2, population:1/2. Confidence: high. Conservative scoring applied per v1.3 rubric.
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