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Sat · 26 Sep 2026

A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.

📅 PUBMED DAILY TRIAGE — 2026-09-26 Window: 2026-09-25T09:00:00Z → 2026-09-26T09:00:00Z (CRDT) Topics scanned: 10 | Articles reviewed: 106 | Candidates evaluated: 106 High priority: 3 | Standard: 38 | Low/archive: 0 | Unsolicited finds: 3 Run status: SUCCESS

🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic

Hematologic malignancies

Hematologic malignancies: No high-priority finds today (best candidate scored 7/10)

CBC-based diagnostics and ML in hematology

CBC-based diagnostics and ML in hematology: No high-priority finds today (best candidate scored 7/10)

Early cancer detection

PM42789831 · Assessing the Utility of the Community Need Priority Index for Breast Cancer Screening. · 6/10 · Score 6/10 [EARLY_CANCER_DETECTION]: Cohort study (Journal Article) matched 'Early cancer detection'. Components — novelty:1/3, relevance:2/3, design:1/2, population:2/2. Confidence: high. Conservative scoring applied per v1.3 rubric. PM42789091 · Urinary Cell-Free DNA Fragmentomics Detects Multiple Urologic Cancers and May Reduce Unnecessary Prostate Biopsies. · 5/10 · Score 5/10 [EARLY_CANCER_DETECTION]: Observational/unspecified (Journal Article) matched 'Early cancer detection'. Components — novelty:1/3, relevance:2/3, design:1/2, population:1/2. Confidence: medium. Conservative scoring applied per v1.3 rubric.

AI and ML in clinical diagnostics

AI and ML in clinical diagnostics: No high-priority finds today (best candidate scored 6/10)

Precision oncology and genomic medicine

Precision oncology and genomic medicine: No high-priority finds today (best candidate scored 7/10)

Novel therapeutics immunotherapy CAR-T

PM42791198 · Efficacy of CAR-T-Cell-Based Immunotherapies in Patients With Glioma: A Systematic Review and Meta-Analysis. · 7/10 · Score 7/10 [NOVEL_TREATMENT]: Meta-analysis (Journal Article) matched 'Novel therapeutics immunotherapy CAR-T'. Components — novelty:1/3, relevance:2/3, design:2/2, population:2/2. Confidence: high. Conservative scoring applied per v1.3 rubric.

Cardiovascular-metabolic GLP-1 SGLT2

Cardiovascular-metabolic GLP-1 SGLT2: No high-priority finds today (best candidate scored 6/10)

Aging longevity and population health

Aging longevity and population health: No high-priority finds today (best candidate scored 6/10)

Rare diseases with high unmet need

Rare diseases with high unmet need: No high-priority finds today (best candidate scored 7/10)

🟢⚪ STANDARD (4-7) — Top by Topic

Hematologic malignancies

PM42790445 · Iberdomide plus daratumumab and dexamethasone versus daratumumab, bortezomib, and dexamethasone in patients with relapsed or refractory multiple myeloma (EXCALIBER-RRMM): an open-label, randomised, controlled, phase 3 trial. · 7/10 · Other PM42787875 · Survival benefit of chemoradiotherapy in limited-stage mantle cell lymphoma: a National Cancer Database analysis. · 6/10 · Treatment Innovation PM42789828 · Daratumumab Plus Bortezomib, Lenalidomide, and Dexamethasone in Newly Diagnosed Multiple Myeloma: Transplant-Ineligible Subgroup Analysis of CEPHEUS. · 6/10 · Other PM42789169 · Comparative efficacy of brain-computer interface-coupled robotic rehabilitation, robot-assisted therapy, and motor imagery for upper-limb motor recovery after stroke: a systematic review and network meta-analysis. · 6/10 · Other PM42787887 · Primary lymphoma of the breast: A case report. · 4/10 · Other

CBC-based diagnostics and ML in hematology

PM42790934 · A Risk Prediction Model Based on Combined CBC and CPD Parameters for Triage of Non-Hodgkin Lymphoma Inpatients. · 7/10 · Diagnostics

AI and ML in clinical diagnostics

PM42787768 · Enhancing weakly supervised 3D medical image segmentation through probabilistic-aware learning. · 6/10 · Diagnostics PM42791089 · Diagnostic performance of artificial intelligence-based coronary artery analysis in the emergency department: A multicenter study. · 6/10 · Diagnostics PM42790900 · Artificial intelligence in perioperative pain: a scoping review protocol. · 6/10 · Diagnostics PM42790865 · Predictive factors of functional recovery in older inpatients: AIRCOT Study. · 6/10 · Diagnostics PM42787752 · Weakly supervised deep learning distinguishes alcohol-associated from metabolic dysfunction-associated steatohepatitis on H&E whole-slide images. · 5/10 · Diagnostics

Precision oncology and genomic medicine

PM42789168 · Application advances of habitat imaging based on CT or PET/CT: a systematic review. · 7/10 · Public Health PM42790864 · LncRNAs and the Cancer Epitranscriptome: Mechanisms and Therapeutic Potential. · 6/10 · Genomics/Precision Medicine PM42790448 · Accelerating equitable cancer genomics and precision oncology in health care and research: a Lancet Oncology Commission. · 6/10 · Genomics/Precision Medicine PM42790332 · PD-L1 alone versus a five-variable genomic-immunotherapy score for predicting response to immune-checkpoint inhibitors in a real-world multi-tumor cohort: a molecular pathology perspective. · 6/10 · Treatment Innovation PM42790325 · Time-dependent impact of programmed death-ligand 1 expression on early progression and long-term response to first-line osimertinib in epidermal growth factor receptor-mutant non-small cell lung cancer. · 6/10 · Other

Novel therapeutics immunotherapy CAR-T

PM42790332 · PD-L1 alone versus a five-variable genomic-immunotherapy score for predicting response to immune-checkpoint inhibitors in a real-world multi-tumor cohort: a molecular pathology perspective. · 6/10 · Treatment Innovation PM42791035 · METLUNG: plasma metabolomic profiling identifies metabolomic signatures associated with immunotherapy outcomes in non-small cell lung cancer. · 6/10 · Treatment Innovation PM42790620 · 2026 Revised Recommendations of The American Association for Thoracic Surgery (AATS) 2023 Expert Consensus Document: Staging and multidisciplinary management of patients with early-stage non-small cell lung cancer. · 6/10 · Treatment Innovation PM42790325 · Time-dependent impact of programmed death-ligand 1 expression on early progression and long-term response to first-line osimertinib in epidermal growth factor receptor-mutant non-small cell lung cancer. · 6/10 · Other PM42788839 · Circadian timing of first-line chemoimmunotherapy is associated with survival in extensive-stage small cell lung cancer. · 5/10 · Treatment Innovation

Cardiovascular-metabolic GLP-1 SGLT2

PM42791090 · Glucagon-Like Peptide-1 Receptor Agonist-Associated Hepatotoxicity. · 6/10 · Prevention PM42790647 · Sleep disturbances and subsequent suicide risk in dementia: A nationwide cohort study. · 6/10 · Prevention PM42790605 · Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in Hidradenitis Suppurativa: A Narrative Review of Emerging Evidence. · 6/10 · Prevention PM42789323 · Association of Neutrophil Percentage-to-Albumin Ratio (NPAR) With Pathological Features and Long-Term Prognosis in Diabetic Kidney Disease: A Cohort Study. · 5/10 · Prevention PM42789307 · An RNA thermogenic therapy to preserve lean mass and enhance metabolic health during GLP-1 weight loss. · 5/10 · Prevention

Aging longevity and population health

PM42789080 · Equivalent Twelve-Month Bone Mineral Density Response to Romosozumab in Patients Aged ≥ 85 Years and  < 85 Years: A Multi-center Real-World Cohort Study (n = 417) from Northern Japan. · 6/10 · Public Health PM42790922 · Study on blueberries, protein and exercise for improving frailty and cardiovascular disease (STRONG): protocol for a parallel-group randomised controlled superiority trial in older Nova Scotians. · 5/10 · Prevention PM42791208 · Effects of Daily Rhythm-Aligned Training on Skeletal Muscle Adaptation in Older Adults: A Randomized Controlled Trial. · 5/10 · Other PM42789559 · Developing Midlife Metacognitive Strategy Training (M-MCST) program: A feasibility study with middle-aged adults to evaluate the design, implementation, and impact of a novel program in fostering healthy cognitive aging. · 5/10 · Public Health PM42789638 · Aortic Stenosis: Diagnosis and Treatment. · 5/10 · Prevention

Rare diseases with high unmet need

PM42790835 · Managing IBS-Like Symptoms in Quiescent Inflammatory Bowel Disease: A Meta-Analysis of Randomized Trials. · 7/10 · Genomics/Precision Medicine PM42790417 · A randomized phase 2 placebo-controlled trial of clobetasol solution for oral chronic graft-versus-host disease therapy. · 7/10 · Other PM42789934 · An Interactive Database of ADAMTS13 Variants Yields Novel Insight into Thrombotic Thrombocytopenic Purpura. · 7/10 · Other PM42791196 · Upadacitinib for Palmoplantar Pustulosis: An Open-label, Assessor-blinded Feasibility Study Using Historic Control Data (JAKPPPOT). · 6/10 · Public Health PM42790161 · Living scaffolds in monogenic genodermatoses: 3D skin models for physiopathology, gene therapy, and drug testing. · 6/10 · Diagnostics

💡 UNSOLICITED FINDS

PM42791219 · Comparative efficacy of ultrasound-guided intra-articular injection of platelet-rich plasma (PRP), hydrolyzed type I collagen, and hyaluronic acid in patients with knee osteoarthritis: a randomized controlled trial. · 7/10 · S: One hundred twenty-six patients completed follow-up. PM42788264 · A clinical study on the efficacy of a novel herbal medicine cocktail in enhancing HIFU treatment for adenomyosis: a pilot randomized controlled trial. · 7/10 · S: The results showed that the VAS scores in the observation group were significantly lower than those in the control group after treatment (p < 0.05). PM42789917 · Epigenetic Insights in Pediatric Multiple Sclerosis: DNA Methylation Highlights an Involvement of Epstein-Barr Virus Infection and Host Immune Networks. · 6/10 · S: Our analysis revealed 55 DMRs, with 28 affecting promoter regions.

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