Cardio-Oncological Sequelae of Autologous Stem Cell Transplantation: Role of Clonal Hematopoiesis in Cardiovascular Risk.
Clonal blood cell mutations emerge as a measurable risk factor for heart problems after stem cell transplants, offering a potential way to identify vulnerable patients early.
Autologous hematopoietic stem cell transplantation is a major milestone in modern oncohematological therapies; however, both in the peritransplant and post-transplant phase, the incidence of cardiovascular (CV) events is markedly higher than in the general population. In recent years, clonal hematopoiesis has emerged as a clinically relevant determinant of adverse CV outcomes.
What the study was
- Study design
- Observational Study
- Category
- Early Detection
- Maturity
- Validated
- Journal
- JACC. Advances
Why it surfaced
Matched watchlist: Early cancer detection (liquid; scored 8/10 based on abstract-level review; design=Observational Study; species=human; flag=PROMISING_PRELIMINARY.
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