Inflammatory Aging-Driven Immune Axis Imbalance and the Mechanisms of Chronicity in Elderly Atopic Dermatitis: A Systematic Review and Meta-Analysis.
Elderly atopic dermatitis (elderly AD) is increasingly recognized as a chronic inflammatory skin disorder with immunopathological features that may differ from those in younger populations. Among these biomarkers, eosinophil levels showed the most consistent association with disease severity across studies, whereas cytokines involved in Th2 and Th17 pathways showed considerable heterogeneity.
Elderly atopic dermatitis (elderly AD) is increasingly recognized as a chronic inflammatory skin disorder with immunopathological features that may differ from those in younger populations. Among these biomarkers, eosinophil levels showed the most consistent association with disease severity across studies, whereas cytokines involved in Th2 and Th17 pathways showed considerable heterogeneity.
What the study was
- Study design
- Systematic review / meta-analysis
- Category
- Public Health
- Maturity
- Potentially Practice-Changing
- Journal
- Immunity, inflammation and disease
Why it surfaced
Systematic review / meta-analysis in Aging, longevity, and population health; species: mixed; scored 8/10 (novelty=2, relevance=2, design=2, pop=2)
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