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‹ Thu · 1 Oct 2026
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Real-world evaluation of 2023-2024 XBB.1.5 mRNA and protein-based COVID-19 vaccine reactogenicity from the randomized BEEHIVE trial.

Novavax's COVID vaccine triggered fewer side effects than Pfizer's in real-world 2023-2024 use.

This randomized controlled trial examined Real-world evaluation of 2023-2024 XBB15 mRNA and protein-based COVID-19 vaccine reactogenicity from the randomized BEEHIVE trial. The PubMed abstract reports There were significant differences in reactogenicity profiles for the 2023-2024 formulations of the NVX and PFZ COVID-19 vaccines, with NVX consistently associated with lower reactogenicity rates than PFZ.

What the study was

Study design
Randomized controlled trial
Population
Human participants or patients described in the abstract
Sample size
453
Category
Other
Maturity
Validated
Journal
Human vaccines & immunotherapeutics

Why it surfaced

Randomized controlled trial with human evidence; score reflects novelty, clinical relevance, design quality, and population or unmet-need value under the v1.3 rubric.

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