📅 PUBMED DAILY TRIAGE — 2026-10-01 Window: 2026-09-30T00:00:00Z → 2026-10-01T09:22:48Z (CRDT) Topics scanned: 10 | Articles reviewed: 124 | Candidates evaluated: 130 High priority: 8 | Standard: 37 | Low/archive: 79 | Unsolicited finds: 7 Run status: SUCCESS
🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic
Hematologic malignancies
Hematologic malignancies: No high-priority finds today (best candidate scored 6/10)
CBC-based diagnostics and machine learning in hematology
CBC-based diagnostics and machine learning in hematology: No high-priority finds today (best candidate scored 0/10)
Early cancer detection
Early cancer detection: No high-priority finds today (best candidate scored 5/10)
AI/ML in clinical diagnostics and imaging
42814997 · Agentic AI for Clinical Outcomes Research, Population Health Management Analyses With Large Administrative Databases, and Generating Epidemiological Estimates of Diseases: Feasibility and Validation Study. · 8/10 · Regarding trust (explainability, transparency, replicability, traceability, and validation), the agentic AI platform generated all source code used for the analyses, which was reviewed and validated for accuracy and appr
Precision oncology and genomic medicine
Precision oncology and genomic medicine: No high-priority finds today (best candidate scored 0/10)
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
42814929 · Giredestrant plus Everolimus in Advanced Breast Cancer. · 9/10 · An all-oral giredestrant-everolimus regimen led to significantly longer progression-free survival than standard endocrine therapy-everolimus among patients with ER-positive, HER2-negative advanced breast cancer who had r
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
42812899 · 5G Cloud-Enabled Telemedicine for Remote Management of Heart Failure Patients With Implantable Cardioverter-Defibrillators: A Multicenter Open-Label Randomized Controlled Trial. · 9/10 · For secondary endpoints, the 5G-CTP group showed greater improvement in life quality at 12 months based on Minnesota Living with Heart Failure Questionnaire (p = 0012) 42815962 · Effect of a walnut-based low carbohydrate diet on fat redistribution and visceral fat accumulation in people with central obesity: A randomized controlled trial. · 9/10 · Although comparison be-tween groups revealed no significant on TLR, VFA and BMI at 12 weeks, comparison within groups showed all decreased with large effect on TLR (η² = 0174, p = 0001), VFA (η² = 0393, p <0001) and BMI
Aging, longevity, and population health
Aging, longevity, and population health: No high-priority finds today (best candidate scored 6/10)
Rare diseases with high unmet need
Rare diseases with high unmet need: No high-priority finds today (best candidate scored 6/10)
🟢⚪ STANDARD (5-7) — Top by Topic
Hematologic malignancies
42813301 · Treatment Patterns and Clinical Outcomes Among Chinese Patients With Newly Diagnosed Multiple Myeloma: A Multicenter Retrospective Study (CHAMP-MM). · 6/10 · Diagnostics 42814327 · Clinical Flow Cytometric Testing in Chronic Lymphocytic Leukemia. · 5/10 · Diagnostics 42814325 · Immunophenotyping of Acute Myeloid Leukemia. · 5/10 · Diagnostics 42814322 · Immunophenotyping of Human B Lymphocytes from Peripheral Blood Mononuclear Cells. · 5/10 · Diagnostics 42814328 · Measurable Residual Disease. · 5/10 · Diagnostics
CBC-based diagnostics and machine learning in hematology
No retained standard-priority finds today.
Early cancer detection
42815529 · Detection Patterns of Breast Cancer Recurrence and Contralateral New Primaries in a Large Integrated Health System. · 5/10 · Early Detection 42814240 · Salivary miRNAs along with p53 and EGFR in oral exfoliated cells: a pilot study on candidate noninvasive biomarkers for the early detection of oral cancer in tobacco users. · 5/10 · Early Detection
AI/ML in clinical diagnostics and imaging
42814672 · Ocular Factors Affecting AI Diagnosis in Diabetic Retinopathy Screening for Resource-Limited Regions: Cross-Sectional Study. · 6/10 · Diagnostics 42813998 · Checklist for Artificial Intelligence in Medical Imaging (CLAIM): Explanation, Elaboration, and Examples. · 5/10 · Diagnostics 42815482 · Doctor of physical therapy students' perceptions of artificial intelligence chatbots versus peer role play for therapeutic interviewing practice. · 5/10 · Diagnostics 42815749 · Feasibility of Functionally Standardized AI-Assisted Coronary CT Angiography Training for Radiology Residents: A Multicenter Randomized Pilot Study. · 5/10 · Diagnostics 42813600 · From signal to reasoning: Computational bottlenecks in the evolution of artificial intelligence in radiology. · 5/10 · Diagnostics
Precision oncology and genomic medicine
42814862 · Interpreting TP53 pathogenic variants in germline testing and cancer genomics: pathogenicity, origin, and clinical actionability. · 5/10 · Diagnostics 42814328 · Measurable Residual Disease. · 5/10 · Diagnostics 42811741 · Optimizing the ER Cutoff in HER2-Positive Breast Cancer: ER ≥ 50% Predicts Low pCR Rates and Resistance to Antibody-Drug Conjugates in the Neoadjuvant Setting. · 5/10 · Treatment Innovation 42814240 · Salivary miRNAs along with p53 and EGFR in oral exfoliated cells: a pilot study on candidate noninvasive biomarkers for the early detection of oral cancer in tobacco users. · 5/10 · Early Detection
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
42811914 · Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Anti-Angiogenic Tyrosine Kinase Inhibitors for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Systematic Review and Single-Arm Meta-Analysis. · 7/10 · Treatment Innovation 42812841 · Optimal, Interpretable, and Personalized Immune Checkpoint Inhibitor Duration in Non-Small Cell Lung Cancer: A Multicenter Real-World Study. · 6/10 · Treatment Innovation 42815983 · Autoimmune Bullous Disorders Associated With Immune Checkpoint Inhibitors: A Retrospective Review of a Single Center Cohort Over the Past Decade. · 5/10 · Treatment Innovation 42812406 · Chimeric Antigen Receptor T-cell therapy in systemic lupus erythematosus and other autoimmune diseases: a literature review. · 5/10 · Treatment Innovation 42814531 · Multi-Omics and Computational Pharmacology Approach With Experimental Validation Reveals the Antiproliferative Activity of Sophoricoside Against Pancreatic Cancer. · 5/10 · Treatment Innovation
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
42811812 · Home-based exercise interventions incorporating cardiac rehabilitation principles for people with cancer: a systematic review and meta-analysis. · 7/10 · Prevention 42815744 · Cardiac Paroxysmal Orthodeoxia Syndrome: A comprehensive process of this challenging disease starting from the clinical suspicion till the therapeutic procedure. · 6/10 · Diagnostics 42812847 · Cardiometabolic and atherosclerotic cardiovascular disease outcomes associated with tirzepatide: insights from a 1-year multicenter observational study. · 6/10 · Prevention 42814410 · A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment. · 5/10 · Diagnostics 42816131 · Akkermansia muciniphila protects diabetes-associated cognitive decline by enhancing leucine catabolism and suppressing neuronal excessive mitophagy. · 5/10 · Treatment Innovation
Aging, longevity, and population health
42814823 · Speech clocks decode dementia phenotypes, social exposome, and biological aging. · 6/10 · Diagnostics 42812846 · Clinical and Molecular Characteristics of Streptococcus dysgalactiae subsp. equisimilis Bacteremia in Japan. · 5/10 · Genomics/Precision Medicine 42814910 · Disentangling Age-Related and Disease-Specific Effects on Upper Cervical Cord Area in Patients With Multiple Sclerosis. · 5/10 · Diagnostics 42812685 · Effects of age on association between obstructive sleep apnea and metabolic syndrome in the Japanese patient population. · 5/10 · Diagnostics 42811797 · From Regenerative to Degenerative Niche: Multicellular Crosstalk and Population Dynamics in Skeletal Muscle Aging. · 5/10 · Public Health
Rare diseases with high unmet need
42815938 · 22q11.2 Deletion Syndrome: A Comprehensive Review for Pediatricians From Diagnosis to Adult Care Transition. · 6/10 · Diagnostics 42814109 · Biphasic SMN condensates safeguard stress-induced cytoplasmic mislocalization of splicing RNPs. · 6/10 · Other 42815744 · Cardiac Paroxysmal Orthodeoxia Syndrome: A comprehensive process of this challenging disease starting from the clinical suspicion till the therapeutic procedure. · 6/10 · Diagnostics 42813231 · Congenital Disorders of Glycosylation (CDG): State of the Art in 2026. · 6/10 · Diagnostics 42813305 · Derivation of a peripheral blood-based transcriptomic risk score for extrapulmonary sarcoidosis. · 6/10 · Genomics/Precision Medicine
💡 UNSOLICITED FINDS
42813573 · One-Year Effects of the FIT FIRST 20 High-Intensity and Multisport Physical Education Program on Physical Fitness and Psychological Outcomes in Early Adolescents: A Cluster-Randomized Controlled Trial. · 10/10 · Other 42811441 · Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults. · 9/10 · Treatment Innovation 42811742 · Real-world evaluation of 2023-2024 XBB.1.5 mRNA and protein-based COVID-19 vaccine reactogenicity from the randomized BEEHIVE trial. · 9/10 · Other 42813454 · PSC-DM: A Validated Clinical Diagnostic Model for Distinguishing Primary From Secondary Sclerosing Cholangitis. · 8/10 · Diagnostics 42812628 · Association between oxytocin exposure in the second stage of labor and postpartum hemorrhage among nulliparous patients with neuraxial analgesia. · 6/10 · Diagnostics 42815960 · Implementing a programme to treat severe acute malnutrition in Indonesia: What works? · 5/10 · Diagnostics 42813193 · Trial of food allergy IgE tests for Eczema Relief (TIGER): study protocol. · 5/10 · Other
📊 TODAY'S BREAKDOWN
- By research category: Diagnostics 23, Early Detection 2, Genomics/Precision Medicine 2, Other 4, Prevention 4, Public Health 1, Treatment Innovation 9
- By evidence maturity: Exploratory 35, Potentially Practice-Changing 1, Validated 9
- By watchlist topic:
- Hematologic malignancies: 15 reviewed / 5 kept / highest 6
- CBC-based diagnostics and machine learning in hematology: 0 reviewed / 0 kept / highest 0
- Early cancer detection: 15 reviewed / 2 kept / highest 5
- AI/ML in clinical diagnostics and imaging: 15 reviewed / 6 kept / highest 6
- Precision oncology and genomic medicine: 15 reviewed / 4 kept / highest 0
- Novel therapeutics: immunotherapy, CAR-T, targeted therapy: 15 reviewed / 7 kept / highest 9
- Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk: 15 reviewed / 9 kept / highest 9
- Aging, longevity, and population health: 15 reviewed / 5 kept / highest 6
- Rare diseases with high unmet need: 15 reviewed / 5 kept / highest 6
- Sentinel: 10 reviewed / 10 kept / highest 10
- By source type: peer_reviewed 45 | preprint 0
- Topics with zero 8+ articles this run: Hematologic malignancies, CBC-based diagnostics and machine learning in hematology, Early cancer detection, AI/ML in clinical diagnostics and imaging, Precision oncology and genomic medicine, Aging, longevity, and population health, Rare diseases with high unmet need
🔧 RUN NOTES
- Complete capped coverage was retrieved for every search; no PMID was missing from ESummary or EFetch.
- CBC/ML returned zero records in both the primary and required fallback query.
- Same-date rerun rebuilt the full daily batch; prior emission did not remove records.
- Duplicate Telegram alerts were not re-emitted.