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‹ Sat · 3 Oct 2026
Promising but preliminary

Clinical Practice Guideline for Systemic Antibacterial and Antifungal Prophylaxis in Pediatric Patients With Cancer and Hematopoietic Cell Transplant Recipients: 2026 Update.

Updated guidelines clarify which pediatric cancer and transplant patients need preventive antibiotics and antifungals, refining decisions for different risk groups.

To provide updated Pediatric Oncology Group of Ontario clinical practice guidelines (CPGs) for systemic antibacterial and antifungal prophylaxis in pediatric patients with cancer and hematopoietic cell transplantation (HCT) recipients. Future research should refine prophylaxis indications for different patient subgroups.

What the study was

Study design
Systematic review
Population
Human participants
Category
Drug Development
Maturity
Validated
Journal
Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Why it surfaced

Conservative v1.3 triage: Systematic review; score 7/10 from novelty 2, relevance 2, design quality 2, and population/unmet need 1.

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