Poliosis predicts durable response to immune-checkpoint blockade in metastatic melanoma: a multicenter cohort study.
Hair whitening (poliosis) appears to predict which melanoma patients respond durably to immunotherapy, potentially guiding treatment decisions.
Immune checkpoint blockade has improved survival outcomes for patients with metastatic melanoma. In this multicenter cohort, poliosis predicted durable response and may complement imaging when clinicians consider treatment duration or early cessation.
What the study was
- Study design
- Observational Study
- Category
- Drug Development
- Maturity
- Exploratory
- Journal
- Journal for immunotherapy of cancer
Why it surfaced
Score 7/10; Design: Observational Study; Topics: Novel therapeutics: immunotherapy, CAR-T, targeted therapy
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