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‹ Wed · 7 Oct 2026
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Dapagliflozin for attenuating early anthracycline-associated cardiac changes (DAPA-AIC): a randomized, double-blind, placebo-controlled trial

A diabetes drug showed promise in reducing early heart damage during chemotherapy, warranting larger studies to confirm potential benefits.

AIMS: To evaluate whether dapagliflozin attenuates early cardiac functional and biomarker changes during anthracycline-based chemotherapy. These findings suggest that dapagliflozin may help attenuate early anthracycline-associated cardiac changes, although larger and longer studies are needed to confirm its clinical benefits and safety.

What the study was

Study design
Randomized Controlled Trial
Population
AIMS: To evaluate whether dapagliflozin attenuates early cardiac functional and biomarker changes du
Category
Genomics/Precision Medicine
Maturity
Potentially Practice-Changing
Journal
Future science OA

Why it surfaced

RCT design; high triage score

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