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‹ Tue · 13 Oct 2026
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Treatment adherence and mental health in people with cystic fibrosis and advanced lung disease treated with elexacaftor/tezacaftor/ivacaftor.

A cystic fibrosis therapy delivered sustained lung benefits and improved quality of life, though some patients experienced manageable neuropsychological side effects.

This PubMed-indexed study examined iNTRODUCTION: Advanced lung disease (ALD) is a leading cause of mortality in cystic fibrosis (CF). The abstract reports eTI provided sustained pulmonary and HRQoL benefits, although persistent neuropsychological side-effects occurred in a subset of participants and were associated with anxiety.

What the study was

Study design
Observational/Cohort Study
Category
Genomics/Precision Medicine
Maturity
Exploratory
Journal
Pulmonology

Why it surfaced

Conservative triage based on the PubMed abstract: observational/cohort study with direct watchlist relevance; score reflects metadata and abstract-level evidence only.

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