Characterization of the morphological, immunophenotypical and cytogenetic features of high-grade B-cell lymphoma with 11q aberration.
To bridge this research gap, we conducted a retrospective analysis of HGBCL with 11q aberration, aiming to elucidate its pathogenesis, clinicopathological features and molecular profiles. The most frequently mutated genes in our cohort are TP53, IGLL5, DDX3X, BTG2, FOXO1, HIST1H1E and MYC.
To bridge this research gap, we conducted a retrospective analysis of HGBCL with 11q aberration, aiming to elucidate its pathogenesis, clinicopathological features and molecular profiles. The most frequently mutated genes in our cohort are TP53, IGLL5, DDX3X, BTG2, FOXO1, HIST1H1E and MYC.
What the study was
- Study design
- Retrospective observational study
- Population
- Human participants; details are provided in the abstract.
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- Histopathology
Why it surfaced
Retained as a 8/10 high-priority candidate for Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma); PubMed metadata and abstract were assessed conservatively.
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