Calreticulin and myeloproliferative neoplasms
Emerging immunotherapy strategies targeting CALR mutations offer a path toward modifying myeloproliferative cancer biology rather than managing symptoms alone.
- Lab
- Preclinical
- Early trials
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- In practice
Oral Versus Injectable Incretin-Based Anti-Obesity Therapies
An oral GLP-1 drug matching injectable versions' effects could help more people stick with obesity treatment by eliminating injection barriers.
Novel or significantly improved treatmentEpigenetic modulation of NKG2D ligands enhances NKG2D-CAR T cell…
Combining epigenetic priming with immune cells shows promise for attacking childhood neuroblastoma, a deadly solid tumor with limited treatment options.
Promising but preliminaryNanoengineered STING agonists for cancer therapy
Nanoparticle delivery of immune-stimulating drugs may transform cold tumors into ones responsive to existing immunotherapies, overcoming past treatment failures.
Near-term implementable findingComparative validation and local adaptation of gastric cancer risk…
Validated risk prediction tools adapted for Chinese populations support earlier gastric cancer detection when treatment is most effective.