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‹ Sat · 20 Jun 2026
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Efficacy of Initiation of Semaglutide versus SGLT2 inhibitors in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Multicenter Propensity-Matched Real-World Study.

Real-world data compares two common medications for fatty liver disease in practical clinical settings, informing treatment choices for this growing health problem.

Real-world multicenter propensity-matched analysis compares semaglutide vs SGLT2 inhibitors for MASLD (metabolic dysfunction-associated steatotic liver disease), an increasingly prevalent condition in cardiometabolic populations. T7 watchlist match; provides practical head-to-head comparative effectiveness data for clinicians.

What the study was

Study design
Multicenter propensity-matched retrospective real-world study
Population
Patients with MASLD initiating semaglutide or SGLT2 inhibitors in multiple centers
Category
Treatment Innovation
Maturity
Exploratory
Journal
Endocrine Practice

Why it surfaced

Clinically useful head-to-head comparison in MASLD. Retrospective propensity-matched design, abstract only. Score 5.

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