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‹ Tue · 7 Jul 2026
Standard addition

[Update: Evolution in the management of metastatic urothelial carcinomas].

Metastatic urothelial carcinoma is undergoing a major therapeutic transformation. The combination of enfortumab-vedotin and pembrolizumab, established in 2024 as the first-line standard of care, has demonstrated impressive survival benefits at 30 months of follow-up and is now the preferred regimen, regardless of cisplatin eligibility.

Metastatic urothelial carcinoma is undergoing a major therapeutic transformation. The combination of enfortumab-vedotin and pembrolizumab, established in 2024 as the first-line standard of care, has demonstrated impressive survival benefits at 30 months of follow-up and is now the preferred regimen, regardless of cisplatin eligibility.

What the study was

Study design
Review
Category
Treatment Innovation
Maturity
Exploratory
Journal
Bulletin du cancer

Why it surfaced

Low-signal Novel therapeutics: immunotherapy, CAR-T, targeted therapy entry (Review design); retained for topic coverage completeness.

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