[Prognostic significance of IKZF1 alterations in acute B-lymphoblastic leukemia and the choice of transplantation strategy].
Gene alterations in Ikaros family zinc finger protein 1 (IKZF1) are common genetic abnormalities in B-cell acute lymphoblastic leukemia (B-ALL) and are closely associated with an increased risk of relapse and poor prognosis. Furthermore, this review aims to provide a clear and actionable blueprint for individualized therapy for B-ALL patients with IKZF1 alterations.
Gene alterations in Ikaros family zinc finger protein 1 (IKZF1) are common genetic abnormalities in B-cell acute lymphoblastic leukemia (B-ALL) and are closely associated with an increased risk of relapse and poor prognosis. Furthermore, this review aims to provide a clear and actionable blueprint for individualized therapy for B-ALL patients with IKZF1 alterations.
What the study was
- Study design
- Not specified
- Category
- Treatment Innovation
- Maturity
- Exploratory
- Journal
- Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
Why it surfaced
Relevant Hematologic malignancies study (promising preliminary signal) meets standard-priority threshold.
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