Effect of endoscopic screening for non-cardia gastric cancer: a 12-year report of a population-based randomized trial.
A 12-year population-based RCT evaluated endoscopic screening for non-cardia gastric cancer, finding a non-significant trend toward reduced cancer incidence (aRR 0.66, 95% CI 0.35-1.22) in screening-compliant participants. While the trial does not yet confirm a definitive mortality benefit, the directional effect supports continued investigation of endoscopic screening in high-risk gastric cancer populations.
A 12-year population-based RCT evaluated endoscopic screening for non-cardia gastric cancer, finding a non-significant trend toward reduced cancer incidence (aRR 0.66, 95% CI 0.35-1.22) in screening-compliant participants. While the trial does not yet confirm a definitive mortality benefit, the directional effect supports continued investigation of endoscopic screening in high-risk gastric cancer populations.
What the study was
- Study design
- Randomized controlled trial
- Sample size
- 668
- Category
- Other
- Maturity
- Potentially Practice-Changing
- Journal
- BMC medicine
Why it surfaced
High-priority Sentinel scan study: promising preliminary signal warrants immediate pipeline escalation.
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