📅 PUBMED DAILY TRIAGE — 2026-07-07 Window: 2026-07-06T00:00:00Z → 2026-07-07T23:59:59Z (CRDT) Topics scanned: 10 | Articles reviewed: 131 | Candidates evaluated: ~150+ High priority: 17 | Standard: 105 | Low/archive: 9 | Unsolicited finds: 10 Run status: SUCCESS Attempt: 2 | Run ID: pubmed-daily-triage-2026-07-07-attempt2-20260707T091439Z
🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic
Hematologic malignancies
- 42409316 · Locoregional recurrence patterns and prognostic outcomes in early-stage natural killer/T- · 10/10 🟠 Novel or significantly improved treatment · CONCLUSION: Asparaginase-based sandwich chemoradiotherapy shows favorable efficacy in early-stage NK
- 42410325 · Efficacy and Safety of the Dual Glucagon-Like Peptide-1 and Glucagon Receptor Agonist Maz · 8/10 ⚪ Promising but preliminary · RESULTS: Nine RCTs (N = 2292; most with low risk of bias) were included.
- 42410301 · Comparative effectiveness of chimeric antigen receptor (CAR) T-cell therapy versus histor · 7/10 🟠 Novel or significantly improved treatment · These results support the benefit of CAR T-cell treatment for patients with R/R aggressive B-cell ly
CBC-based diagnostics and machine learning in hematology
No high-priority finds today (best candidate scored 7/10)
Early cancer detection
- 42409933 · Serum miR-181a-5p, miR-214-3p, and miR-223-3p in epithelial ovarian cancer. · 7/10 🔴 Early cancer detection or prevention · Serum miR-181a-5p and miR-223-3p are significantly downregulated in EOC and exhibit moderate discrim
- 42410425 · Liquid biopsy-based multi-omics approach for early detection of hepatocellular carcinoma · 6/10 🔴 Early cancer detection or prevention · In high-risk individuals, the model demonstrated 92.9% (95% CI: 64.2%-99.6%) sensitivity, 90.6% (95%
- 42409118 · Cytisine for Smoking Cessation Within a Lung Cancer Screening Program: Results From the I · 6/10 🔴 Early cancer detection or prevention · The cytisine group showed greater reduction in cigarette consumption (23.4% vs.
- 42406326 · Circulating cfDNA CD86 methylation is associated with durable response to atezolizumab-be · 6/10 🔴 Early cancer detection or prevention · RESULTS: High-cfDNA independently predicted shorter OS (median 13.0 vs.
AI/ML in clinical diagnostics and imaging
- 42410010 · Implementation of an ai-enabled multimodal emergency care system is associated with impro · 8/10 🟢 Near-term implementable finding · The AI models demonstrated robust performance during validation (deterioration prediction AUC 0.89;
Precision oncology and genomic medicine
No high-priority finds today (best candidate scored 7/10)
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
- 42410390 · Comparative efficacy and safety of first-line immunotherapy- and targeted therapy-based r · 9/10 ⚪ Promising but preliminary · In safety analyses, EGFR-targeted agents showed relatively favorable profiles in selected outcomes.
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
- 42410344 · Sustainable diets and functional foods for the prevention of cardio-metabolic diseases an · 8/10 🟢 Near-term implementable finding · The rapid increase in industrialization and urbanization has been linked to environmental degradatio
- 42410309 · Cardiovascular Outcomes With Tirzepatide Versus GLP-1 Receptor Agonists in Overweight or · 8/10 ⚪ Promising but preliminary · In exploratory subgroup analyses, patients with type 2 diabetes showed lower estimated risks of all-
- 42409691 · Cardiovascular Drug Access in Australia and New Zealand: New PBS and PHARMAC Listings, 20 · 7/10 🟠 Novel or significantly improved treatment · RESULTS: Five new cardiovascular drugs were PBS-listed (inclisiran, mavacamten, tafamidis, icosapent
Aging, longevity, and population health
- 42406878 · Patients' Experiences of Nurse-Led eHealth Interventions for Chronic Heart Failure: Quali · 8/10 🟢 Near-term implementable finding · The findings suggest that future intervention design should better address patient heterogeneity, te
Rare diseases with high unmet need
- 42407012 · Polatuzumab Vedotin Plus Rituximab, Gemcitabine, and Oxaliplatin in Relapsed or Refractor · 10/10 🟠 Novel or significantly improved treatment · RESULTS: In total, 255 patients were randomly assigned to receive Pola-R-GemOx (n = 129) or R-GemOx
- 42404437 · Efficacy and safety of pegzilarginase in patients below 2 years of age with arginase 1 de · 9/10 🟠 Novel or significantly improved treatment · INTERPRETATION: In patients with ARG1-D <2 years of age, pegzilarginase demonstrated pharmacokinetic
Sentinel scan
- 42410446 · Mortality effect of albumin fluid resuscitation in adults with septic shock: a systematic · 8/10 🟢 Near-term implementable finding · A mortality benefit is therefore plausible, but the supporting evidence is indirect and imprecise (G
- 42410417 · Effect of endoscopic screening for non-cardia gastric cancer: a 12-year report of a popul · 8/10 ⚪ Promising but preliminary · A subgroup analysis of the screening group restricted to participants who complied with screening pr
🟢⚪ STANDARD (5-7) — Top by Topic
Hematologic malignancies
- 42410272 · Prognostic impact of KMT2A-PTD in acute myeloid leukemia in the NGS era: a mult · 7/10 · Treatment Innovation
- 42409743 · [Current status and progress in the diagnosis and treatment of monomorphic epit · 7/10 · Treatment Innovation
- 42409675 · Myelodysplastic Syndrome With Autoimmune Disease: Clinical and Molecular Feature · 7/10 · Treatment Innovation
- 42409674 · The Prognostic Role of Interim [18F]FDG PET/CT in Diffuse Large B-Cell Lymphoma: · 7/10 · Treatment Innovation
- 42410474 · Tibial plateau depression and widening as predictors of meniscal and ligamentous · 6/10 · Treatment Innovation
CBC-based diagnostics and machine learning in hematology
- 42404557 · Comparative predictive value of nine inflammation-derived haematological indices · 7/10 · Diagnostics
Early cancer detection
- 42410441 · Interoperability of two commercial kits in detecting high oncogenic human papil · 5/10 · Early Detection
- 42409329 · Electronic Health Record-Embedded Automated Patient Outreach to Increase Comple · 5/10 · Early Detection
- 42407247 · Propylene carbonate-PVDF-HFP/MXene-based self-powered biosensor for auxiliary d · 5/10 · Early Detection
- 42409187 · Update on Rectal Neuroendocrine Neoplasms. · 5/10 · Early Detection
- 42407200 · Cationic nanotrap curbs UVB-induced cutaneous photodamage via exosomal cfNA cap · 5/10 · Early Detection
AI/ML in clinical diagnostics and imaging
- 42410243 · Brain aging in Type II GM1 gangliosidosis. · 7/10 · Diagnostics
- 42410204 · Application of deep machine learning in dental education: a systematic review of · 7/10 · Diagnostics
- 42409885 · Precision lung cancer classification using convolutional neural networks with e · 7/10 · Diagnostics
- 42410391 · Factors associated with delayed diagnosis of fibrotic interstitial lung disease: · 6/10 · Diagnostics
- 42410387 · Multisequence MRI and clinical data-based deep learning radiomics model for pre · 6/10 · Diagnostics
Precision oncology and genomic medicine
- 42409117 · Genomic Landscape and Clinical Impact of MTAP Loss in Driver-Positive NSCLC: In · 7/10 · Genomics/Precision Medicine
- 42407139 · A morphology-guided ViT-CNN approach for the detection of lung and colon cancer · 6/10 · Genomics/Precision Medicine
- 42407009 · Afatinib for Advanced Cancers Carrying an EGFR, HER2, or HER3 Mutation: An Open · 6/10 · Genomics/Precision Medicine
- 42405329 · Tumor suppressor network dysregulation in neuroblastoma: molecular mechanisms an · 6/10 · Genomics/Precision Medicine
- 42410432 · AI-driven neoantigen identification: a comprehensive review from somatic variant · 5/10 · Genomics/Precision Medicine
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
- 42410247 · Visible light reprograms MSCs and T cells into tumor-suppressive states via OPN · 7/10 · Treatment Innovation
- 42409796 · Tumor-draining lymph nodes shape the tumor microenvironment through enrichment o · 7/10 · Treatment Innovation
- 42410370 · FZD5 drives macrophage-mediated immunomodulation and predicts prognosis in glio · 6/10 · Treatment Innovation
- 42409786 · Soluble HER2 promotes chronic antigen-mediated CD8(+) T-cell dysfunction and lim · 6/10 · Treatment Innovation
- 42407398 · Precision targeting in biliary tract cancer therapy: A geographical, target, and · 6/10 · Treatment Innovation
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
- 42410308 · A Cross-Nationally Validated Nomogram for Cardiometabolic Multimorbidity in Ove · 7/10 · Prevention
- 42410329 · GLP-1 Receptor Agonists for Weight Loss and Risk of Major Safety Outcomes: A Mu · 6/10 · Prevention
- 42410316 · Real-World Effectiveness and Safety of Tirzepatide in Type 1 Diabetes and Obesi · 6/10 · Prevention
- 42410298 · Epidemiological Studies on Type 2 Diabetes Using the German Disease Analyser Da · 6/10 · Prevention
- 42410080 · SGLT2 inhibition induces autophagic flux blockade and sensitizes pancreatic can · 6/10 · Prevention
Aging, longevity, and population health
- 42406913 · Artificial Intelligence-Assisted Screening for Patients With Diabetic Retinopath · 7/10 · Public Health
- 42406807 · Is correction for gradient nonlinearity necessary in a brain diffusion tensor MR · 7/10 · Public Health
- 42403561 · Effect Heterogeneity of CPAP on MACE by Nocturnal Hypoxia Burden in Older Adults · 7/10 · Public Health
- 42403177 · Adipose tissue-derived stem cell exosomes enhance skin barrier function and show · 7/10 · Public Health
- 42404938 · HIV testing history and positivity among repeat testers and first-time testers i · 6/10 · Public Health
Rare diseases with high unmet need
- 42405844 · A Phase 1 Study of Convection-Enhanced Delivery of Intraputaminal AAV2-GDNF in · 7/10 · Drug Development
- 42405669 · AAV8-Mediated Retinal PD-L1 Gene Transfer Attenuates Experimental Autoimmune Uv · 7/10 · Drug Development
- 42407257 · Non-immune causes of fetal anemia. · 6/10 · Drug Development
- 42406834 · Discordance in orphan drug approvals between the U.S. Food and Drug Administrat · 6/10 · Drug Development
- 42404303 · Efficacy assessment in trials of complex and rare diseases: a comparison between · 6/10 · Drug Development
Sentinel scan
- 42410493 · Comprehensive and low-cost machine learning models for predicting MASLD prevale · 6/10 · Other
- 42410440 · Eye-tracking phenotypes reveal clinically meaningful heterogeneity of attention · 6/10 · Other
- 42410426 · A comprehensive plasma-based approach to thromboinflammation in bladder cancer: · 6/10 · Other
- 42410488 · From manual entry to machine precision: challenges and evolution of metadata sc · 5/10 · Other
- 42410462 · A systems herbal-to-molecule and transcriptomic strategy identifies emodin as an · 5/10 · Other
💡 UNSOLICITED FINDS
- 42410446 · Mortality effect of albumin fluid resuscitation in adults with septic shock: a systematic · 8/10 · A mortality benefit is therefore plausible, but the supporting evidence is indirect and imprecise (G
- 42410417 · Effect of endoscopic screening for non-cardia gastric cancer: a 12-year report of a popul · 8/10 · A subgroup analysis of the screening group restricted to participants who complied with screening pr
📊 TODAY'S BREAKDOWN
By research category:
- Treatment Innovation: 30
- Diagnostics: 16
- Drug Development: 15
- Prevention: 15
- Public Health: 15
- Early Detection: 15
- Genomics/Precision Medicine: 15
- Other: 10
By evidence maturity:
- Exploratory: 86
- Validated: 30
- Potentially Practice-Changing: 15
By source type:
- peer_reviewed: 131
By watchlist topic (reviewed / kept / highest score):
- Hematologic malignancies: 15 reviewed / 13 kept / 10/10 best
- CBC-based diagnostics and machine learning in hematology: 1 reviewed / 1 kept / 7/10 best
- Early cancer detection: 15 reviewed / 12 kept / 7/10 best
- AI/ML in clinical diagnostics and imaging: 15 reviewed / 14 kept / 8/10 best
- Precision oncology and genomic medicine: 15 reviewed / 15 kept / 7/10 best
- Novel therapeutics: immunotherapy, CAR-T, targeted therapy: 15 reviewed / 15 kept / 9/10 best
- Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk: 15 reviewed / 13 kept / 8/10 best
- Aging, longevity, and population health: 15 reviewed / 15 kept / 8/10 best
- Rare diseases with high unmet need: 15 reviewed / 14 kept / 10/10 best
- Sentinel scan: 10 reviewed / 10 kept / 8/10 best
Topics with zero 8+ articles this run:
- CBC-based diagnostics and machine learning in hematology (best: 7/10)
- Precision oncology and genomic medicine (best: 7/10)
🔧 RUN NOTES
- Attempt 2 of 3: Fixed 15 articles with single-sentence plain_summary from attempt 1 (replaced raw abstract excerpts with proper 2-sentence summaries)
- Window: 2026-07-06 00:00:00 → 2026-07-07 23:59:59 UTC on CRDT (no expansion needed; sufficient articles found)
- T2 (CBC/ML hematology): Only 1 result — low publication volume for this topic on this date
- No truncation beyond per-topic 15-candidate cap
- All topic candidate PMIDs fully accounted for in search logs
- No missing PMIDs after retry