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52 papers read · 52 surfaced · 1 stood out
Today's lead · Treatment Innovation
Enabling access to talicabtagene autoleucel in relapsed/refractory…
A humanized CAR-T therapy approved in India shows successful implementation across multiple centers, potentially expanding access to this treatment for blood cancers globally.
Atharva Karulkar, Hasmukh Jain, Neeraj Sidharthan et al. · Blood cancer journal
9/10
Impact score
Time to impact (est.)
- Lab
- Preclinical
- Early trials
- Late trials
- In practice
Novel or significantly improved treatment
Englumafusp alfa plus glofitamab in B cell non-Hodgkin lymphoma
A new combination therapy offers hope for patients with aggressive B-cell lymphomas who don't respond to standard treatments.
Novel or significantly improved treatmentDose-reduced (24 Gy) involved-site radiotherapy combined with…
Lower-dose radiation combined with immunotherapy provided lasting disease control in localized lymphomas, suggesting a gentler approach may work.
Near-term implementable findingSafety and efficacy of immune checkpoint inhibitors as a bridge to…
Immune therapy before stem cell transplant in Hodgkin lymphoma patients showed good survival and disease control without excess side effects.
Standard additionLong-Term Outcomes of Neoadjuvant Chemotherapy (NAC) Prior to…
Neoadjuvant chemotherapy followed by bladder-sparing treatment offered durable remission for some muscle-invasive bladder cancer patients over long term.