Organotropism-specific circulating tumor cells profiles: Morphology and heterotypic clustering predict metastatic sites in liquid biopsy of solid tumors.
Circulating tumor cell profiles predict where cancers are likely to spread, enabling targeted prevention strategies.
While circulating tumor cells (CTCs) are the primary drivers of metastatic dissemination, the mechanisms governing their organotropism remain poorly characterized. These findings position multimodal CTC analysis as a liquid biopsy tool for early metastasis site forecasting, guiding precision interventions.
What the study was
- Study design
- Cohort study
- Population
- Cancer/disease patients
- Sample size
- 82
- Category
- Early Detection
- Maturity
- Validated
- Journal
- European journal of cancer (Oxford, England : 1990)
Why it surfaced
Matched topic(s): Early cancer detection, Precision oncology and genomic medicine. Study design: Cohort study. Score 5/10.
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