Food Effects on the Pharmacokinetics of Single Dose and Steady-State Ralinepag, a Novel Oral Prostacyclin Agonist, in Healthy Volunteers.
Food doesn't significantly affect the blood levels or safety of a new pulmonary hypertension medication, simplifying patient dosing.
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder characterized by pathological pulmonary vascular remodeling leading to right heart failure. Food status did not significantly affect the PK or safety of ralinepag XR.
What the study was
- Study design
- Cohort study
- Category
- Prevention
- Maturity
- Validated
- Journal
- American journal of cardiovascular drugs : drugs, devices, and other interventions
Why it surfaced
Matched topic(s): Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk. Study design: Cohort study. Score 6/10.
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