Transcriptomic Profiling of Adhesion GPCRs in Pancreatic Adenocarcinoma Identifies ADGRG7 and ADGRF1 as Novel Diagnostic Biomarkers and Therapeutic Targets.
Pancreatic adenocarcinoma (PAAD) is characterized by a desmoplastic, profoundly immunosuppressive tumor microenvironment (TME). Adhesion G protein-coupled receptors (aGPCRs) regulate cell-matrix interactions and immune modulation, yet their specific roles in PAAD remain poorly understood.
Pancreatic adenocarcinoma (PAAD) is characterized by a desmoplastic, profoundly immunosuppressive tumor microenvironment (TME). Adhesion G protein-coupled receptors (aGPCRs) regulate cell-matrix interactions and immune modulation, yet their specific roles in PAAD remain poorly understood.
What the study was
- Study design
- Journal Article (unspecified)
- Category
- Treatment Innovation
- Maturity
- Exploratory
- Journal
- Anticancer Res
Why it surfaced
Matched watchlist topic 'Precision oncology and genomic medicine'. Study design: Journal Article (unspecified). Score: 8/10 (N:3, R:3, D:1, P:1).
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