Coated or chewable Aspirin and a hybrid air pollution mitigation strategy in patients with atherosclerotic disease: Rationale and Design of the COATED-AIR Randomized Trial.
BACKGROUND: Although enteric-coated aspirin is widely used instead of chewable formulations in patients with atherosclerotic cardiovascular diseases (ASCVD), its effects on cardiovascular and gastrointestinal outcomes re CONCLUSION: COATED-AIR will determine whether aspirin coating affects its safety or effectiveness, and whether individual-level strategies can mitigate cardiovascular risks from air pollution in patients with ASCVD. Full text review required for further details.
BACKGROUND: Although enteric-coated aspirin is widely used instead of chewable formulations in patients with atherosclerotic cardiovascular diseases (ASCVD), its effects on cardiovascular and gastrointestinal outcomes re CONCLUSION: COATED-AIR will determine whether aspirin coating affects its safety or effectiveness, and whether individual-level strategies can mitigate cardiovascular risks from air pollution in patients with ASCVD. Full text review required for further details.
What the study was
- Study design
- Randomized Controlled Trial
- Population
- Patient/participant population (size not extracted)
- Category
- Drug Development
- Maturity
- Potentially Practice-Changing
- Journal
- European heart journal. Cardiovascular pharmacotherapy
Why it surfaced
Scored 8/10 (Randomized Controlled Trial; novelty=2, relevance=3, design_quality=2, population_or_unmet_need=1). HIGH priority.
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