Real-world Experience with Sotorasib in KRAS G12C-Mutated Advanced…
AIM: Sotorasib is an oral, potent, selective inhibitor. The UK RWE aligns with the results of CodeBreaK 200.
- Lab
- Preclinical
- Early trials
- Late trials
- In practice
Association of robot-assisted radical prostatectomy with improved…
OBJECTIVE: To evaluate the efficacy of robot-assisted radical prostatectomy (RARP) combined with androgen deprivation therapy (ADT) vs. CONCLUSION: RARP combined with ADT was significantly associated with improved oncological outcomes in patients with OmPCa, and this association was independent of baseline characteristics; however, this finding is limite.
Standard additionDiagnostic Accuracy of AI in Prediction and Assessment of Compromised…
BACKGROUND: Vascular compromise remains the leading cause of free-flap failure. Nevertheless, the low certainty of evidence, substantial heterogeneity, and limited external validation indicate that prospective multicenter validation and standardized reporting are required before routine clinical imp.
Standard additionIntracorporeal Versus Extracorporeal Anastomosis in Minimally…
BACKGROUND: Minimally invasive right colectomy is a standard treatment for Crohn's disease. ICA significantly reduced overall postoperative complications compared with ECA (OR: 0.44, 95% CI: 0.28-0.70; CONCLUSION: ICA was associated with fewer postoperative complications than ECA during minimally invasive ileo.
Standard additionKetamine versus Etomidate as an induction agent for tracheal intubation
BACKGROUND: Emergency tracheal intubation is a critical and life-saving intervention. REGISTRATION: PROSPERO (CRD420261361259).