Evaluating the predictive value of multiple rounds of faecal haemoglobin measurement for the prediction of advanced neoplasia and colorectal cancer: an analysis of data from the Dutch national colorectal cancer screening programme.
OBJECTIVE: Faecal haemoglobin (f-Hb) concentrations from two screening rounds improve colorectal cancer (CRC) risk prediction, but the value of longer longitudinal data remains uncertain. Targeted referral of the highest risk individuals enables earlier detection with limited impact on colonoscopy capacity, supporting personalised CRC screening strategies.
OBJECTIVE: Faecal haemoglobin (f-Hb) concentrations from two screening rounds improve colorectal cancer (CRC) risk prediction, but the value of longer longitudinal data remains uncertain. Targeted referral of the highest risk individuals enables earlier detection with limited impact on colonoscopy capacity, supporting personalised CRC screening strategies.
What the study was
- Study design
- Diagnostic Validation Study
- Population
- n=70
- Sample size
- 70
- Category
- Early Detection
- Maturity
- Validated
- Journal
- BMJ open gastroenterology
Why it surfaced
Scored 8/10 (Diagnostic Validation Study; novelty=2, relevance=3, design_quality=2, population_or_unmet_need=1). HIGH priority via EARLY_CANCER_DETECTION flag.
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