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‹ Thu · 24 Sep 2026
Standard addition

Sustained proton-pump inhibitor exposure and incident age-related macular degeneration: a new-user, population-based cohort study.

OBJECTIVE: Proton-pump inhibitors (PPIs) may disrupt lysosomal acidification, a pathway implicated in age-related macular degeneration (AMD) pathogenesis. The consistency of the active-comparator findings supports the potential specificity of this association and warrants further investigation to determine its clinical implications.

OBJECTIVE: Proton-pump inhibitors (PPIs) may disrupt lysosomal acidification, a pathway implicated in age-related macular degeneration (AMD) pathogenesis. The consistency of the active-comparator findings supports the potential specificity of this association and warrants further investigation to determine its clinical implications.

What the study was

Study design
Cohort Study
Category
Treatment Innovation
Maturity
Validated
Journal
BMJ open ophthalmology

Why it surfaced

Score 8/10: Cohort Study matching topic 'Cardiovascular-metabolic GLP-1 SGLT2'

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