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‹ Fri · 25 Sep 2026
Standard addition

Expert consensus on clinical trials for use of systemic therapy in patients with hepatocellular carcinoma undergoing surgical and locoregional therapies.

BACKGROUND: Advances in systemic therapy for advanced hepatocellular carcinoma (HCC) have fuelled a growing interest in evaluating these therapies in earlier stages of disease. The recommended primary outcome for combination trials was progression-free survival and overall survival, with an alpha-recycling strategy.

BACKGROUND: Advances in systemic therapy for advanced hepatocellular carcinoma (HCC) have fuelled a growing interest in evaluating these therapies in earlier stages of disease. The recommended primary outcome for combination trials was progression-free survival and overall survival, with an alpha-recycling strategy.

What the study was

Study design
Observational Study
Category
Treatment Innovation
Maturity
Validated
Journal
Gut

Why it surfaced

Topic: Novel therapeutics immunotherapy CAR-T; Score 6/10 → STANDARD priority

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