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‹ Sun · 4 Oct 2026
Near-term implementable finding

Aetiology-Specific Pancreatic Enzyme Dose Requirements and Treatment Outcomes in Pancreatic Exocrine Insufficiency: The Multicentre EURO-PEI Registry

BACKGROUND: Pancreatic exocrine insufficiency (PEI) is a maldigestion syndrome leading to symptoms and nutritional deficiencies. RESULTS: Among 1015 patients, PEI was secondary to chronic pancreatitis in 496 (48.9%), pancreatectomy in 185 (18.2%), pancreatic cancer in 174 (17.1%), and acute pancreatitis in 95 (9.4%).

BACKGROUND: Pancreatic exocrine insufficiency (PEI) is a maldigestion syndrome leading to symptoms and nutritional deficiencies. RESULTS: Among 1015 patients, PEI was secondary to chronic pancreatitis in 496 (48.9%), pancreatectomy in 185 (18.2%), pancreatic cancer in 174 (17.1%), and acute pancreatitis in 95 (9.4%).

What the study was

Study design
Multicenter cohort study
Population
Patients
Sample size
1015
Category
Treatment Innovation
Maturity
Exploratory
Journal
United European gastroenterology journal

Why it surfaced

Matched Rare diseases with high unmet need; Multicenter cohort study; human study; score 8/10 (n=2 r=2 dq=2 pop=2)

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