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‹ Sun · 4 Oct 2026
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Obstetric and thrombotic outcomes among pregnant patients with myeloproliferative neoplasms: a propensity score matched real-world analysis

We performed a multicenter retrospective propensity score-matched cohort study using the TriNetX database to evaluate maternal, obstetric, and thrombotic outcomes among pregnant patients with MPN compared with matched non-MPN controls. Pregnancies in patients with MPN are associated with significantly increased maternal, obstetric, and venous thrombotic complications, highlighting the need for multidisciplinary management and individualized thromboprophylaxis strategies.

We performed a multicenter retrospective propensity score-matched cohort study using the TriNetX database to evaluate maternal, obstetric, and thrombotic outcomes among pregnant patients with MPN compared with matched non-MPN controls. Pregnancies in patients with MPN are associated with significantly increased maternal, obstetric, and venous thrombotic complications, highlighting the need for multidisciplinary management and individualized thromboprophylaxis strategies.

What the study was

Study design
Multicenter cohort study
Population
Patients
Sample size
4563
Category
Other
Maturity
Exploratory
Journal
Annals of hematology

Why it surfaced

Matched Hematologic malignancies; Multicenter cohort study; human study; score 9/10 (n=2 r=3 dq=2 pop=2)

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