Dynamic Circulating Tumor DNA Methylation Monitoring Guiding…
Blood tests that detect cancer DNA after surgery help doctors catch returning colorectal cancer earlier and treat it more effectively before it spreads.
- Lab
- Preclinical
- Early trials
- Late trials
- In practice
A distinct CAR-T cell phenotype mediates therapeutic response at limited doses.
A specific type of CAR-T immune cell signature predicts treatment success regardless of dose, potentially enabling effective therapy with fewer manufactured cells.
Novel or significantly improved treatmentImpact of EBV Status and Histology on Patient Outcomes with…
Nivolumab-based immunotherapy works better than standard chemotherapy for advanced Hodgkin lymphoma in all patient groups, including those historically hardest to treat.
Near-term implementable findingClinical Trial
Resmetirom safely improves liver scarring and metabolic markers in mid-stage MASH disease, confirming its value for approved patients.
Promising but preliminaryAdaptor-mediated rewiring of FLT3 signaling engages p38 MAPK to…
Blocking a stress pathway alongside standard leukemia drugs suppresses drug-resistant AML in lab models, suggesting a rational new combination approach.